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Updated: Mar 24, 2026

Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
The Role of Platelets in Venous Thromboembolism
Silvia Montoro-García1, Marc Schindewolf2, Sophia Stanford3
1Department of Cardiovascular Risk, Faculty of Health Sciences, UCAM Universidad Católica San Antonio de Murcia, Campus de los Jerónimos, Guadalupe, Murcia, Spain.
Abstract:
Multiple factors contribute to the risk of venous thromboembolism (VTE). Platelets have attracted much interest in arterial cardiovascular disease, whereas their role in VTE has received much less attention. Recent evidence suggests that platelets may play a more important role in VTE than previously anticipated. This review discusses the mechanisms that link platelets with venous thrombotic disease and their potential applications as novel risk factors for VTE. In addition, animal studies and randomized clinical trials that highlight the potential effect of antiplatelet therapy in venous thrombosis are evaluated to assess the role of platelets in VTE. The clinical significance of platelets for VTE risk assessment in specific patient cohorts and their role as a suitable therapeutic target for VTE prevention is acknowledged. The role of platelets in VTE is a promising field for future research.
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