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Imaging the hamster flank organ by an ultrasonic technique: a new approach to animal tests
C Combettes1, V Durand-Seme, B Querleux
1Laboratoire de Recherches de L'Oreal, Departement de Biophysique, Aulnay-sous-Bois, France.
The British Journal of Dermatology
|December 1, 1989
Abstract:
Images of the hamster flank organ were obtained in vivo by high resolution ultrasound (B-scan). The planimetric measurements of the ultrasonic image that determined the size of the flank organ, with a reproducibility of about 10%, highly correlated with the measurements of histological sections. This new method provides a simple and non-invasive method for determining the size of the hamster flank organ after various treatments which does not involve the killing of the animal under investigation.