Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cell-based therapy injections for the management of knee osteoarthritis: The ESSKA-ICRS consensus. Recommendations using the RAND/UCLA appropriateness method for different clinical scenarios.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2026
Same author

Ewing sarcoma of the Mandible: a systematic review and pooled survival analysis.

Oral oncology·2026
Same author

Erythropoietin and Skeletal Cells CrossTalks in Physiology and Disease.

Current opinion in endocrine and metabolic research·2026
Same author

Impaired collagen deposition in the absence of ERp44.

iScience·2026
Same author

Bone and Infections: An Osteoimmunological Interplay.

International journal of molecular sciences·2026
Same author

Preclinical Tumorigenicity Study of an Advanced Therapy Medicinal Product for Diffuse Cartilage Lesions in an Osteoarthritic Environment.

Cells·2026

Related Experiment Video

Updated: Mar 24, 2026

Tricolor Transgenic Murine Model for Studying Growth Plate Injury
07:58

Tricolor Transgenic Murine Model for Studying Growth Plate Injury

Published on: September 6, 2024

1.3K

Analysis of Mouse Growth Plate Development.

Laura Mangiavini1, Christophe Merceron1,2,3, Ernestina Schipani1

  • 1Department of Orthopaedic Surgery, Department of Medicine, Division of Endocrinology and Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan.

Current Protocols in Mouse Biology
|March 2, 2016
PubMed
Summary

Mice are crucial for studying skeletal development and bone diseases. This study details common methods for analyzing the mouse fetal growth plate, aiding research into cartilage and bone conditions.

Keywords:
cartilagecell cultureendochondral bone developmentmousestaining

More Related Videos

Culturing and Measuring Fetal and Newborn Murine Long Bones
06:58

Culturing and Measuring Fetal and Newborn Murine Long Bones

Published on: April 26, 2019

8.8K
Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
07:23

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification

Published on: December 3, 2016

12.5K

Related Experiment Videos

Last Updated: Mar 24, 2026

Tricolor Transgenic Murine Model for Studying Growth Plate Injury
07:58

Tricolor Transgenic Murine Model for Studying Growth Plate Injury

Published on: September 6, 2024

1.3K
Culturing and Measuring Fetal and Newborn Murine Long Bones
06:58

Culturing and Measuring Fetal and Newborn Murine Long Bones

Published on: April 26, 2019

8.8K
Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
07:23

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification

Published on: December 3, 2016

12.5K

Area of Science:

  • Skeletal Biology
  • Developmental Biology
  • Orthopedics

Background:

  • The mouse is a key model organism for investigating skeletal development and diseases.
  • Understanding bone and cartilage development is essential for treating skeletal disorders.
  • Endochondral ossification forms the majority of the skeleton.

Purpose of the Study:

  • To detail in vivo and in vitro techniques for analyzing the mouse fetal growth plate.
  • To provide a resource for researchers studying skeletal development and disease.
  • To support the investigation of novel therapeutic strategies for bone and cartilage conditions.

Main Methods:

  • In vivo analysis of the mouse fetal growth plate.
  • In vitro techniques for studying chondrocytes and osteoblasts.
  • Detailed examination of mesenchymal condensation differentiation.

Main Results:

  • Established protocols for analyzing mouse fetal growth plate development.
  • Demonstrated methods for assessing cellular differentiation in skeletal development.
  • Provided a comprehensive overview of current laboratory techniques.

Conclusions:

  • The described methods are vital for advancing the understanding of skeletal development.
  • These techniques facilitate research into the pathophysiology of cartilage and bone diseases.
  • The study supports the assessment of innovative treatments for skeletal conditions.