Related Experiment Video
Updated: Mar 24, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
Paediatric respiratory infections
1School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital, Subiaco, Australia mark.everard@uwa.edu.au.
Insights
Pediatric pulmonary infections significantly impact child mortality globally. This review highlights recent research on host-microorganism interactions in lung infections in children.
Area of Science:
- Pediatric Pulmonology
- Microbiology
- Infectious Diseases
Background:
- Pulmonary infections are a leading cause of death and illness in infants and children worldwide.
- Understanding the complex interplay between the human host and microorganisms is crucial for addressing this health burden.
Purpose of the Study:
- To review key findings from peer-reviewed articles on pediatric pulmonary infections published in the 12 months preceding the 2015 European Respiratory Society International Congress.
- To provide insights into the host-microorganism interactions in the context of lung infections in children.
Main Methods:
- A review of peer-reviewed articles on pediatric pulmonary infections.
- Presentation of findings during a Paediatric Clinical Year in Review session at a major respiratory congress.
Main Results:
- Recent research offers new insights into the dynamics of microbial populations within the respiratory tract.
- Understanding these interactions is key to developing effective strategies against pediatric lung infections.
Conclusions:
- Continued research into host-microbe interactions is essential for reducing the global burden of pediatric pulmonary infections.
- Advances in understanding these complex relationships can inform clinical practice and public health interventions.
Abstract:
Pulmonary infections remain a major cause of infant and child mortality worldwide and are responsible for a substantial burden of morbidity. During the 2015 European Respiratory Society International Congress in Amsterdam, some of the main findings from peer-reviewed articles addressing this topic that were published in the preceding 12 months were reviewed in a Paediatric Clinical Year in Review session. The following article highlights some of the insights provided by these articles into the complex interactions of the human host with the extensive and dynamic populations of microorganisms that call an individual "home".
More Related Videos
Related Concept Videos
Pulmonary Cycle: Exhalation
Microbiota of the Respiratory Tract
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Common Respiratory Disorders
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Influenza

