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Updated: Mar 24, 2026
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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
632
[Multiple reoperation of recurrent maxillofacial huge dermatofibrosarcoma protuberans]
Summary
Surgical treatment for maxillofacial dermatofibrosarcoma protuberans, even with Mohs micrographic surgery (MMS), can lead to repeated relapses at surgical margins. Expanded resection and free flap grafting are recommended, alongside radiotherapy and close follow-up.
Area of Science:
- Dermatology
- Surgical Oncology
- Maxillofacial Surgery
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin tumor.
- Maxillofacial DFSP presents unique challenges due to anatomical complexity and cosmetic concerns.
Observation:
- A case of recurrent, large maxillofacial DFSP treated surgically multiple times between 2004 and 2011.
- Treatments included extensive resection, Mohs micrographic surgery (MMS), and free flap grafting.
- Complete tumor removal was achieved in each surgery, with successful skin graft survival.
Findings:
- Despite complete resection, the tumor repeatedly recurred, with all recurrences at the MMS surgical margins.
- Recurrence intervals varied from 7 months to over 5 years, with a trend towards longer intervals over time.
Implications:
- Expanded resection is crucial for early-stage maxillofacial DFSP.
- For advanced cases, combining expanded resection with MMS is recommended.
- Free flap grafting is preferred over myocutaneous flaps for reconstruction.
- Postoperative radiotherapy, vigilant follow-up, and early intervention are vital for managing recurrent DFSP.
