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Related Experiment Video

Updated: Mar 24, 2026

Author Spotlight: Methanol-Based Whole-Mount Preparation for the Investigation of Retinal Ganglion Cells
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Methanol Induced Toxic Amblyopia--A Case Report.

A H Khan1, M F Rahaman, R I Mollah

  • 1Dr Abed Hussain Khan, Medical Officer, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ
|March 3, 2016
PubMed
Summary
This summary is machine-generated.

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This study shows that prompt treatment with steroids and vitamins can effectively restore vision in patients suffering from severe methanol-induced optic neuropathy, a serious complication of consuming toxic alcohol.

Area of Science:

  • Ophthalmology
  • Toxicology
  • Neurology

Background:

  • Methanol poisoning can cause severe vision loss due to optic nerve damage.
  • Early diagnosis and intervention are crucial for visual recovery.

Observation:

  • A 28-year-old male presented with profound vision loss in both eyes after consuming homemade alcohol.
  • Fundus examination revealed pale optic discs, indicative of optic neuropathy.

Findings:

  • Treatment with intravenous and oral corticosteroids, along with Hydroxycobalamine (Vitamin B1) and Folinic Acid, led to significant visual improvement.
  • Visual acuity recovered from no light perception to 6/18 in the affected eyes within four weeks.

Implications:

  • This case highlights the efficacy of a combined therapeutic approach for methanol-induced optic neuropathy.

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  • Aggressive treatment can prevent permanent vision loss and improve patient outcomes.