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Updated: Mar 24, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Routine Screening for Callosal Dysgenesis in the Second Trimester Is Achievable With Intensive Training
Ilona Lavender1, Peter R Coombs2, Keith Van Haltren3
1Department of Ultrasound, Monash Health, Melbourne, Victoria, Australia ilona.lavender@monashhealth.org.
Intensive training significantly improved the visualization of the corpus callosum during routine second-trimester ultrasounds. This enhanced imaging is achievable without significantly increasing examination time, providing valuable diagnostic information.
Area of Science:
- Medical imaging
- Fetal ultrasonography
- Neurosonography
Background:
- The corpus callosum is a critical brain structure evaluated during prenatal screening.
- Direct visualization of the corpus callosum during routine second-trimester sonography can be challenging.
Purpose of the Study:
- To assess the feasibility of routine direct visualization of the corpus callosum during second-trimester sonography.
- To determine the impact of intensive training on corpus callosum visualization rates.
- To evaluate the time required to obtain sagittal corpus callosum images.
Main Methods:
- Retrospective cohort study design.
- Evaluation of 150 second-trimester sonographic scans before and after intensive training.
- Assessment of corpus callosum image quality and visualization rates.
Main Results:
- Complete visualization of the corpus callosum increased significantly after training (23% to 71%, P < .0001).
- The mean time to obtain corpus callosum views remained similar before (53.4 seconds) and after (56.2 seconds) training.
- Intensive training led to a substantial improvement in the detection rate of the corpus callosum.
Conclusions:
- Direct sagittal view of the corpus callosum is achievable during routine second-trimester sonography with appropriate training.
- This visualization can be accomplished without adding significant time to the examination.
- Improved visualization of the corpus callosum provides valuable additional information for fetal morphologic scans.
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