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Factors Influencing Cognitive Function in Subjects With COPD
Ersel Dag1, Emel Bulcun2, Yakup Turkel1
1Department of Neurology.
The Montreal Cognitive Assessment (MoCA) is more effective than the Mini Mental State Examination (MMSE) for detecting cognitive dysfunction in Chronic Obstructive Pulmonary Disease (COPD) patients. MoCA scores correlate with exercise capacity and disease severity.
Area of Science:
- Pulmonary Medicine
- Neuroscience
- Geriatrics
Background:
- Cognitive impairment is common in Chronic Obstructive Pulmonary Disease (COPD).
- Assessing cognitive function is crucial for managing COPD patients.
- The Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) are commonly used cognitive screening tools.
Purpose of the Study:
- To evaluate the association between cognitive function and clinical parameters (age, pulmonary function, comorbidity, 6-min walk distance) in COPD.
- To compare the efficacy of MMSE and MoCA in identifying cognitive dysfunction in COPD patients.
Main Methods:
- 52 stable COPD patients were enrolled.
- Cognitive function assessed using MMSE and MoCA.
- Clinical data including pulmonary function, comorbidity index, and 6-min walk distance were collected.
Main Results:
- MoCA demonstrated a wider range and greater variability in scores compared to MMSE.
- Both MMSE and MoCA scores correlated with 6-min walk distance and comorbidity index.
- MoCA scores, unlike MMSE, remained significantly associated with 6-min walk distance and comorbidity index after multivariate analysis.
Conclusions:
- MoCA appears to be a more sensitive tool than MMSE for screening cognitive impairment in COPD.
- Integrating cognitive assessments into routine COPD evaluations can enhance patient care.
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