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Enterovirus D68 Infection in an Adult.

Nicholas S Ward1, Brenna L Hughes1, Leonard A Mermel2

  • 1Nicholas S. Ward is an attending physician, Division of Pulmonary, Critical Care, and Sleep Medicine, Rhode Island Hospital, and an associate professor, Warren Alpert Medical School, Brown University, Providence, Rhode Island. Brenna L. Hughes is an associate professor, Warren Alpert Medical School, and director, Division of Maternal Fetal Medicine fellowship, Women and Infants Hospital, Providence, Rhode Island. Leonard A. Mermel is an attending physician, Division of Infectious Diseases, Rhode Island Hospital, and a professor, Warren Alpert Medical School, Brown University.

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Summary
This summary is machine-generated.

A pregnant woman experienced severe respiratory illness from enterovirus D68 (EV-D68). This case highlights pregnant women as a potential sentinel group for EV-D68, similar to influenza virus surveillance.

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Enterovirus D68 (EV-D68) is a respiratory virus that can cause severe illness.
  • Pregnant women are a population of interest for respiratory pathogen surveillance due to potential impacts on maternal and fetal health.

Observation:

  • The first confirmed US case of severe EV-D68 respiratory infection in an adult was a pregnant woman.
  • She presented with cough, headache, dyspnea, hypoxia, and required intensive care with noninvasive ventilation.

Findings:

  • Nasopharyngeal swab analysis confirmed enterovirus D68 infection.
  • The patient recovered fully, had an uneventful delivery, and resumed normal activities.

Implications:

  • Pregnant women may serve as a sentinel group for monitoring EV-D68 outbreaks.
  • This finding supports enhanced surveillance of EV-D68 in pregnant populations, analogous to influenza monitoring.