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[Automated instruments for clinical laboratory--its past and future]
Rinsho Byori. the Japanese Journal of Clinical Pathology
|December 1, 1989
Summary
Clinical laboratory automation has advanced significantly since the Autoanalyzer and AGA-Autochemist inventions. These systems evolved from basic analyzers to sophisticated multi-channel instruments for diverse diagnostic applications.
Area of Science:
- Clinical laboratory science
- Medical diagnostics
- Automation technology
Context:
- The evolution of clinical laboratory automation began with the invention of the Autoanalyzer (flow system) in 1953 and the AGA-Autochemist (discrete system).
- Subsequent advancements have transformed these initial systems into sophisticated multi-channel instruments.
- These developments are crucial for modern clinical laboratory examinations.
Purpose:
- To review the historical development of clinical laboratory automation instruments.
- To track advancements in flow and discrete system technologies over time.
- To document progress reported at the Japan Society for Clinical Laboratory Automation meetings and in its journal.
Summary:
- The Autoanalyzer evolved from mono-channel to multi-channel, incorporating various methods and computer aid for applications in chemistry, hematology, and immunochemistry.
- The AGA-Autochemist, initially a complex system, spurred the development of refined discrete system instruments now used across multiple fields.
- This review chronicles instrument development in five-year intervals based on Japanese Society for Clinical Laboratory Automation publications.
Impact:
- Significant contributions to the efficiency and scope of clinical laboratory examinations.
- Enabled broader application of automated analysis in diverse medical fields.
- Laid the groundwork for current advanced diagnostic technologies in clinical labs.