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[Drugs and pregnancy].

M Bonati, R Bortolus, F Marchetti

    Medicina (Florence, Italy)
    |July 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Pregnant women use an average of 4.7 medications, commonly vitamins, iron, analgesics, antiemetics, and antacids. However, varying study methods prevent a complete global picture of drug use during pregnancy.

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    Area of Science:

    • Pharmacovigilance
    • Maternal Health
    • Drug Safety

    Context:

    • Assessing global drug utilization patterns in pregnant populations.
    • Reviewing 13 identified studies through manual and computer searches.
    • Highlighting the heterogeneity of data collection and reporting across studies.

    Purpose:

    • To evaluate the current state of knowledge on medication use during pregnancy worldwide.
    • To identify common drug classes used by pregnant women.
    • To determine the feasibility of creating a comprehensive drug utilization profile.

    Summary:

    • Pregnant women, on average, used 4.7 drugs, with vitamins, iron, analgesics, antiemetics, and antacids being most frequent.
    • Significant variations in study parameters (date, country, population size, habits, characteristics) hindered a unified analysis.

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  • The review underscored the critical need for standardized, ongoing surveillance of drug use in pregnancy.
  • Impact:

    • Identifies critical data gaps in understanding medication safety during pregnancy.
    • Emphasizes the necessity for systematic, long-term monitoring of drug consumption in pregnant individuals.
    • Provides a foundation for improving future research methodologies and public health strategies in maternal pharmacovigilance.