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Super-resolution Imaging of the Natural Killer Cell Immunological Synapse on a Glass-supported Planar Lipid Bilayer
Published on: February 11, 2015
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A vision of KIR variation at super resolution
John A Hammond1, Mary Carrington2,3, Salim I Khakoo4
1The Pirbright Institute, Pirbright, Woking, Surrey, UK.
Immunology
|March 4, 2016
Summary
The Ninth Killer Cell Immunoglobulin-Like Receptor (KIR) Workshop highlighted KIR diversity and function. Advances in sequencing and bioinformatics deepen our understanding of KIR evolution and disease roles.
Area of Science:
- Immunology
- Genetics
Background:
- The Ninth Killer Cell Immunoglobulin-Like Receptor (KIR) Workshop convened in 2015.
- Key themes included the significant diversity of KIR and its functional implications.
Framework:
- Exploring the genetic diversity and evolution of KIR.
- Investigating KIR functions, including specificity for MHC and peptide ligands.
Implementation:
- Utilizing novel sequencing technologies.
- Applying new bioinformatics techniques for data analysis.
Implications:
- Refining models of KIR's role in disease pathogenesis.
- Generating novel research ideas in the expanding field of KIR research.
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