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Updated: Mar 24, 2026

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
Published on: September 11, 2018
Sympathetic Nervous System, Hypertension, Obesity and Metabolic Syndrome
Gino Seravalle1, Guido Grassi2,3
1Cardiology Department, S. Luca Hospital, Istituto Auxologico Italiano, Piazza Brescia 20, 20149, Milan, Italy. g_seravalle@yahoo.com.
Abstract:
Experimental and clinical studies have clearly shown the role of the sympathetic nervous system in the pathophysiology of several cardiovascular and non-cardiovascular diseases. This short review will be aimed at focusing and discussing the new information collected on two specific clinical conditions such as obesity and metabolic syndrome. The paper will briefly describe the four main mechanisms that represent the common link between these two pathophysiological conditions and that through the sympathetic nervous system contribute to increase the cardiovascular risk.
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