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Endoscopic ultrasonography in pediatric patients--Experience from a tertiary care center in India
Ramit Mahajan1, Ebby George Simon2, Ashok Chacko1
1Department of Gastroenterology, Christian Medical College, Vellore, 632 004, Tamil Nadu, India.
Insights
Endoscopic ultrasound (EUS) is safe and feasible in pediatric patients, offering valuable diagnostic information for gastrointestinal and pancreaticobiliary conditions. This study confirms its positive clinical impact in children.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Endoscopy
- Diagnostic Imaging
Background:
- Limited data exists on the role of endoscopic ultrasound (EUS) in pediatric gastrointestinal (GI) disease management.
- EUS is widely used in adult GI care.
Purpose of the Study:
- To evaluate the indications, safety, and clinical impact of EUS in children.
- To assess the diagnostic yield of EUS in pediatric patients.
Main Methods:
- Retrospective analysis of records for children (<18 years) who underwent EUS between January 2006 and September 2014.
- Review of diagnostic and therapeutic EUS procedures, including EUS-guided fine needle aspiration cytology (FNAC).
Main Results:
- 123 EUS procedures were performed on 121 children, primarily for pancreaticobiliary system evaluation.
- EUS diagnosed various conditions including chronic pancreatitis, pancreatic masses, insulinomas, choledocholithiasis, and GI tumors.
- EUS demonstrated a positive clinical impact in 35.5% of pediatric patients, with a low rate of minor adverse events.
Conclusions:
- Endoscopic ultrasound (EUS) is a feasible and safe procedure for pediatric patients.
- EUS provides crucial diagnostic information that positively influences the clinical management of children with GI and pancreaticobiliary disorders.
Background And Aims:
Although endoscopic ultrasound (EUS) is used in the management of various gastrointestinal (GI) diseases in adults, data on its role in children is limited. This study evaluated the indications, safety, and impact of EUS in children.
Methods:
Records of children (<18 years age) who underwent EUS between January 2006 and September 2014 were reviewed retrospectively and analyzed.
Results:
One hundred and twenty-one children (70 males, 51 females) aged 15.2 ± 2.9 years (mean ± SD) underwent 123 diagnostic (including fine needle aspiration cytology (FNAC) in 7) and 2 therapeutic EUS procedures. Conscious sedation was used in 81 procedures (65%) and general anesthesia in 44 (35%). The pancreaticobiliary system was evaluated in 114 (118 procedures), mediastinum in 5, and stomach in 2 patients. EUS diagnosed chronic pancreatitis (21 patients), pancreatic necrosis (1), splenic artery pseudoaneurysm (1), gastric varix (1), pseudocysts (3), insulinomas (2), other pancreatic masses (2), choledocholithiasis (2), choledochal cysts (2), portal biliopathy (1), esophageal leiomyoma (1), gastric neuroendocrine tumor (NET) (1), and GI stromal tumor in stomach (1). EUS-guided FNAC was positive in four of seven patients (two had tuberculosis, one pancreatic solid pseudopapillary tumor, and one gastric NET). Three patients had minor adverse events. EUS had a positive clinical impact in 43 (35.5%) patients.
Conclusions:
EUS is feasible and safe in children. It provides valuable information that helps in their clinical management.
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