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Parental Factors Associated with Intrauterine Growth Restriction

Monica G Haşmaşanu, Sorana D Bolboaca, Tudor C Drugan

    Srpski Arhiv Za Celokupno Lekarstvo
    |March 8, 2016
    PubMed

    Insights

    Maternal hypertension is a significant risk factor for intrauterine growth restriction (IUGR) in Romanian newborns. Lower parental age was observed in IUGR cases, but hypertension was the key predictor.

    Area of Science:

    • Obstetrics and Gynecology
    • Neonatology
    • Public Health

    Background:

    • Linear growth failure in infants can stem from various factors, including parental influences.
    • Intrauterine growth restriction (IUGR) is a critical concern in neonatal health, necessitating the identification of associated risk factors.

    Purpose of the Study:

    • To investigate parental risk factors associated with intrauterine growth restriction (IUGR) in a Romanian infant population.
    • To evaluate the impact of maternal and paternal characteristics on IUGR development in a tertiary care setting.

    Main Methods:

    • A retrospective matched case-control study was conducted.
    • Data were collected from 4,790 infants admitted to a neonatal ward in North-Western Romania between January 2012 and June 2014.
    • Infants with IUGR were compared to a control group based on parental and infant characteristics.

    Main Results:

    • Mothers of infants with IUGR were significantly younger (p=0.041) and had higher rates of hypertension (p<0.05).
    • Fathers of infants with IUGR were also significantly younger (p=0.0278).
    • Hypertension in mothers was identified as a significant risk factor for IUGR (OR=2.4, 95% CI [1.3-4.5]).

    Conclusions:

    • Maternal hypertension is a significant risk factor for IUGR.
    • While younger parental age was noted, it was not a significant independent predictor.
    • The study highlights the importance of managing maternal hypertension to prevent IUGR.
    Abstract

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