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Updated: Mar 24, 2026

Preparation of Gynura bicolor DC samples for High-Resolution Tandem Mass Spectrometry
Published on: February 2, 2024
[Chemical Constituents from Sphagneticola trilobata]
Objective:
To study the chemical constituents of the whole plant of Sphagneticola trilobata.
Methods:
The compounds were isolated and purified by column chromatography and their structures were determined by spectroscopic techniques.
Results:
Three lignans, two indolics and two phenolic glycosides were isolated from the whole plant of Sphagneticola trilobata and identified as syringaresinol-4-O-β-D-glucopyranoside(1), pinoresinol-4-sulfate(2), pinoresinol-4-O-β-D-glucopyranoside(3), 1H-indole-3-carboxylic acid (4), 1H-indole-3-carbaldehyde(5), 2,6-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside (6), and 3,5-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside (7).
Conclusion:
Compounds 1 - 7 are isolated from the genus Wedelia for the first time. Compound 4 demonstrates significant inhibitory activity against α-glucosidase.
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