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Updated: Aug 7, 2026

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Immunofluorescent Detection of Two Thymidine Analogues CldU and IdU in Primary Tissue
Published on: December 7, 2010
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A fluorescent surrogate of thymidine in duplex DNA
Guillaume Mata1, Olivia P Schmidt1, Nathan W Luedtke1
1Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. nathan.luedtke@chem.uzh.ch.
Abstract:
is a new fluorescent thymidine mimic composed of 2'-deoxyuridine fused to dimethylaniline. exhibits the same pKa and base pairing characteristics as native thymidine residues, and its fluorescence properties are highly sensitive to nucleobase ionization, base pairing and metal binding.
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