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Updated: Mar 24, 2026

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
Published on: May 10, 2017
Percutaneous Selective Neuromodulation via Monopolar Radiofrequency for Glabellar Lines: A Case Study
Introduction:
Injectable botulinum toxin is a safe, effective, and popular therapy that blocks neural impulses to achieve a desired effect. Using monopolar RF, percutaneous selective neuromodulation can achieve a similar but more persistent effect.
Methods:
Bilateral treatment was performed on a woman (48 years of age) to ablate the angular nerves of the face, inhibiting muscular function and reduce the appearance of glabellar lines. The cannula was inserted at the mid-pupillary line and advanced toward the lateral border of the nose. After isolating the nerve via low-level stimulation, anesthetic was given through a port in the cannula and energy was applied; tissue temperature of 85 °C was maintained for 70 seconds.
Results:
Full ablative lesioning of the angular nerve of the patient was achieved and function was therapeutically inhibited with minimal pain. Results have persisted for more than two years.

