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Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

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Published on: July 21, 2013

Complete middle cerebral artery block without brain infarction.

Sunil Pradhan¹, Surjyaprakash S Choudhury, Vimal Kumar Paliwal

¹Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Neurology India

|March 9, 2016

Summary

This study reports a rare case of progressive supranuclear palsy with an absent right middle cerebral artery (MCA). Despite the missing artery, no brain infarct was observed, prompting discussion on brain circulation development.

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Area of Science:

Neurology
Neurovascular Imaging
Embryology

Background:

Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease.
Cerebral artery anatomy can exhibit congenital variations.
Vascular imaging plays a crucial role in diagnosing cerebrovascular conditions.

Observation:

A patient diagnosed with progressive supranuclear palsy presented with an incidental finding.
The right middle cerebral artery (MCA) was congenitally absent.
No evidence of acute or old infarct was detected in the MCA's typical territory.

Findings:

Advanced imaging techniques, including magnetic resonance angiography and computed tomography angiography, did not reveal significant collateral circulation to the affected brain region.
The absence of the right MCA in this PSP patient is a unique presentation.
The study explores potential embryological explanations for this rare vascular anomaly.

Implications:

This case highlights the brain's potential capacity for adaptation and compensation in the absence of major cerebral arteries.
Understanding rare vascular variations is essential for accurate diagnosis and treatment planning in neurological disorders.
Further research into cerebral circulation embryogenesis may elucidate mechanisms behind such anomalies.