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[Keratoacanthoma centrifugum marginatum].

H Hackel1, G Burg, W Lechner

  • 1Dermatologische Klinik und Poliklinik, Julius-Maximilians-Universität Würzburg.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|December 1, 1989
PubMed
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Keratoacanthoma centrifugum marginatum (KCM) is a rare skin tumor. Early surgical excision is recommended due to its continuous spread and lack of spontaneous remission.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma.
  • Understanding its unique clinical and histological features is crucial for diagnosis and management.

Observation:

  • The study describes clinical and histological features of KCM based on three cases and literature review.
  • KCM exhibits continuous centrifugal spread and lacks spontaneous remission.
  • Histological examination reveals an 'iceberg-like' growth pattern.

Findings:

  • KCM is a highly differentiated, biologically benign, non-metastasizing tumor.
  • Distinct clinical behavior includes centrifugal spread and no spontaneous remission.
  • Subclinical growth pattern observed histologically.

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Implications:

  • Early surgical excision is the recommended treatment for KCM.
  • Accurate diagnosis based on clinical and histological features is vital.
  • Further research into KCM's pathogenesis may reveal novel therapeutic targets.