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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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The current approach of atrial fibrillation management

Anish Amin1, Aseel Houmsse1, Abiodun Ishola1

  • 1Department of Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, Ohio, USA.

Avicenna Journal of Medicine
|March 9, 2016
PubMed

Insights

Atrial fibrillation (AF), a common heart rhythm disorder, poses risks for stroke and death, especially with heart failure. This review covers advances in AF management, anticoagulation, and new treatments.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Internal Medicine

Background:

  • Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia.
  • Increasing diagnoses are linked to aging populations and better management of chronic conditions.
  • AF significantly elevates the risk of stroke, systemic embolism, and mortality, particularly in patients with comorbidities like heart failure.

Purpose of the Study:

  • To review recent advancements in cardiology for managing atrial fibrillation.
  • To discuss the evolution of anticoagulation strategies for AF patients.
  • To highlight new oral anticoagulants, reversal agents, and non-pharmacological treatments.

Main Methods:

  • Literature review of landmark trials and clinical practice guidelines.
  • Analysis of recent developments in AF management.
  • Evaluation of anticoagulation therapies and alternative treatment options.

Main Results:

  • Significant progress has been made in both acute and long-term AF management.
  • Novel oral anticoagulants (NOACs) and their reversal agents represent a major therapeutic advance.
  • Non-pharmacological options and the utility of implantable loop recorders are increasingly recognized.

Conclusions:

  • Current cardiology practices offer improved AF management strategies.
  • Anticoagulation remains a cornerstone, with newer agents offering safer and more effective options.
  • A comprehensive approach integrating pharmacological and non-pharmacological methods is crucial for optimal AF patient outcomes.

Keywords:
Antiarrhythmicanticoagulationatrial fibrillationdrugs and ablation

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