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Updated: Mar 24, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
Ischemic cardiomyopathy revealed by central retinal artery occlusion (CRAO)
Ihsen Zairi1, Khadija Mzoughi1, Zouhayer Jnifene1
1Department of Cardiology, Habib Thameur public hospital, Bab el Fallah, Tunis, Tunisia.
Insights
A sudden visual loss in one eye can signal a serious underlying heart condition. This case highlights central retinal artery occlusion as a precursor to undiagnosed ischemic cardiomyopathy.
Area of Science:
- Ophthalmology
- Cardiology
- Vascular Medicine
Background:
- Central retinal artery occlusion (CRAO) is a critical condition often associated with cardiovascular risk factors.
- Early detection of vascular events is crucial for preventing severe morbidity.
Observation:
- A 54-year-old male smoker presented with acute, unilateral visual loss.
- Ophthalmic examination revealed a characteristic cherry-red spot in the macula of the affected eye.
Findings:
- Diagnostic workup, including fluorescein angiography and cervical color Doppler, confirmed CRAO.
- Subsequent investigations uncovered a previously undiagnosed ischemic cardiomyopathy.
Implications:
- This case underscores the importance of a comprehensive cardiovascular assessment in patients presenting with CRAO.
- Ocular symptoms can serve as an early indicator of silent ischemic cardiomyopathy, necessitating prompt cardiac evaluation and management.
Abstract:
Here we report a case of central retinal artery occlusion revealing an ischemic cardiomyopathy. A 54-year old smoker man presented at the hospital because of sudden visual loss in his left eye. There was cherry-red spot in the macula in his left eye. We performed a fluorescein angiogram and cervical color Doppler. Later investigations revealed an ischemic cardiomyopathy undiagnosed until then.
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