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Updated: Mar 24, 2026

Visualization and Quantification of Mesenchymal Cell Adipogenic Differentiation Potential with a Lineage Specific Marker
Published on: March 31, 2018
Metallomics approach to changes in element concentration during differentiation from fibroblasts into adipocytes by
Yasumitsu Ogra1, Shu Nagasaki, Ayako Yawata
1Department of Toxicology and Environmental Health, Graduate School of Pharmaceutical Sciences, Chiba University.
Abstract:
We aimed to establish an element array analysis that involves the simultaneous detection of all elements in cells and the display of changes in element concentration before and after a cellular event. In this study, we demonstrated changes in element concentration during the differentiation of 3T3-L1 mouse fibroblasts into adipocytes. This metallomics approach yielded unique information of cellular response to physiological and toxicological events.

