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Gabapentin for Chronic Refractory Cancer Cough
Shrikant Atreya1, Gaurav Kumar1, Soumitra Shankar Datta1
1Department of Palliative Care and Psycho-oncology, Tata Medical Center, Kolkata, West Bengal, India.
Indian Journal of Palliative Care
|March 11, 2016
Summary
Gabapentin effectively treated chronic refractory cough caused by lung mass compression. This medication reduced cough intensity, duration, and frequency in a patient with vagal hypersensitivity.
Area of Science:
- Neurology
- Pulmonology
- Pharmacology
Background:
- Chronic refractory cough is often linked to vagal sensory neuropathy or hypersensitivity.
- Gabapentin has demonstrated efficacy in treating neuropathic conditions and symptoms of neural origin.
Observation:
- A case report details a patient experiencing chronic refractory cough.
- The cough was attributed to a soft tissue lung mass compressing mediastinal structures.
Findings:
- The patient received gabapentin treatment.
- Successful treatment resulted in significant reductions in cough intensity, duration, and frequency.
Implications:
- Gabapentin may be a viable therapeutic option for chronic refractory cough associated with vagal hypersensitivity and mediastinal compression.
- This case highlights the potential of gabapentin in managing complex cough etiologies.
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