Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preparation and properties of copper-oil-based nanofluids.

Nanoscale research letters·2011
Same author

Ordered gelation of chemically converted graphene for next-generation electroconductive hydrogel films.

Angewandte Chemie (International ed. in English)·2011
Same author

A highly selective and sensitive on-off sensor for silver ions and cysteine by light scattering technique of DNA-functionalized gold nanoparticles.

Chemical communications (Cambridge, England)·2011
Same author

The remarkable enhancement of CO-pretreated CuO-Mn2O3/γ-Al2O3 supported catalyst for the reduction of NO with CO: the formation of surface synergetic oxygen vacancy.

Chemistry (Weinheim an der Bergstrasse, Germany)·2011
Same author

Application of multiwall carbon nanotubes-based matrix solid phase dispersion extraction for determination of hormones in butter by gas chromatography mass spectrometry.

Journal of chromatography. A·2011
Same author

[Association of HLA DRB1 polymorphism with susceptibility to myelodysplastic syndrome and aplastic anemia in Chinese Han population].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics·2011
Same journal

Mapping the 3D Chromosome Organization of a Biosynthetic Gene Cluster by Capture Hi-C (CHi-C).

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Mapping the 3D Chromosome Organization of Streptomyces by Hi-C.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

CUT&Tag Epigenomic Profiling of Biosynthetic Gene Clusters in Arabidopsis thaliana.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Rhizobium rhizogenes-Mediated Hairy Root Transformation Protocol for Lotus japonicus and Other Legumes.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Characterization of Bioactive Saponins from Sea Cucumbers.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Methods for Functional Validation of Terpenoid Metabolic Clusters in Nicotiana benthamiana and Aspergillus oryzae.

Methods in molecular biology (Clifton, N.J.)·2026
See all related articles

Related Experiment Video

Updated: Mar 24, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

61.0K

Optogenetics: Basic Concepts and Their Development.

Yong Ku Cho1,2, Dan Li3

  • 1Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT, USA. cho@engr.uconn.edu.

Methods in Molecular Biology (Clifton, N.J.)
|March 12, 2016
PubMed
Summary
This summary is machine-generated.

Optogenetics uses light-activated proteins to control neural activity, transforming neuroscience. This technology

Keywords:
ChannelrhodopsinLight-activated proteinOptogeneticsPhotoreceptorProtein engineering

More Related Videos

Building a Simple and Versatile Illumination System for Optogenetic Experiments
06:41

Building a Simple and Versatile Illumination System for Optogenetic Experiments

Published on: January 12, 2021

4.6K
Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications
11:13

Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications

Published on: February 19, 2017

10.2K

Related Experiment Videos

Last Updated: Mar 24, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

61.0K
Building a Simple and Versatile Illumination System for Optogenetic Experiments
06:41

Building a Simple and Versatile Illumination System for Optogenetic Experiments

Published on: January 12, 2021

4.6K
Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications
11:13

Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications

Published on: February 19, 2017

10.2K

Area of Science:

  • Neuroscience
  • Biotechnology
  • Molecular Biology

Background:

  • Optogenetics, utilizing light-gated ion channels, has revolutionized the control of neural activity.
  • The application of light-activated proteins has expanded beyond neuroscience, leveraging diverse photoreceptors and biophysical data.

Purpose of the Study:

  • To discuss the origins and evolution of optogenetics.
  • To highlight the fundamental principles underpinning optogenetics' efficacy.
  • To review advancements in optogenetic concepts over the last decade and explore future directions.

Main Methods:

  • Review of foundational research and biophysical characterization of photoreceptors.
  • Analysis of the development and diversification of optogenetic tools and applications.
  • Synthesis of current knowledge and future trends in the field.

Main Results:

  • Optogenetics provides precise control over biological processes using light.
  • The technology's versatility is driven by natural photoreceptor diversity and extensive biophysical understanding.
  • Significant progress has been made in developing and applying optogenetic tools.

Conclusions:

  • Optogenetics is a powerful and versatile technology with a transformative impact on neuroscience.
  • Continued research into photoreceptors and biophysical characterization will drive further innovation.
  • The field is poised for continued expansion and novel applications.