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Primary cutaneous anaplastic large-cell lymphoma: a case report.
Can Cao1, Kang Zeng1, Menglei Wang1
1Department of dermatology, Nan Fang Hospital, Guangzhou, China.
Dermatologic Therapy
|March 13, 2016
Summary
Primary cutaneous anaplastic large-cell lymphoma (PCALCL) in a teen resolved with chemotherapy and skin grafting. This combined approach offers a promising treatment for PCALCL, preventing recurrence.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Primary cutaneous anaplastic large-cell lymphoma (PCALCL) is a CD30+ lymphoproliferative skin disorder.
- PCALCL often presents as ulcerated nodules with slow progression and potential for recurrence.
Observation:
- A 16-year-old male presented with PCALCL manifesting as single facial nodules, ulceration, keloid, and scab.
- The patient exhibited a positive response to systemic chemotherapy and dermatoplasty.
Findings:
- The combined treatment of chemotherapy, surgical excision, and dermatoplasty proved effective for PCALCL.
- Post-treatment evaluation showed no relapse of the primary lesion or organ involvement.
Implications:
- Systemic chemotherapy combined with surgical excision and dermatoplasty is a viable treatment strategy for PCALCL.
- This multimodal approach can lead to successful recovery and improved patient confidence.