Related Experiment Video
Updated: Mar 24, 2026
07:40
A Murine Model of Subarachnoid Hemorrhage
Published on: November 21, 2013
20.7K
Equine anaesthesia-associated mortality: where are we now?
Alexandra H A Dugdale1, Polly M Taylor2
1Faculty of Health and Life Sciences, Institute of Veterinary Science, University of Liverpool, Neston, UK.
Veterinary Anaesthesia and Analgesia
|March 14, 2016
Summary
Equine anesthesia mortality has decreased, with newer agents like isoflurane reducing cardiac arrests. However, catastrophic fractures now pose the greatest risk during horse anesthesia recovery.
Area of Science:
- Veterinary Anesthesiology
- Equine Medicine
Background:
- General anesthesia in horses carries inherent mortality risks.
- The Confidential Enquiry into Perioperative Equine Fatalities (CEPEF) aimed to improve outcomes.
- Assessing long-term trends in equine anesthesia mortality is crucial for veterinary practice.
Purpose of the Study:
- To conduct a literature review on equine anesthesia-associated mortality.
- To evaluate changes in horse anesthesia mortality over the past 20 years since CEPEF.
Main Methods:
- Comprehensive literature search using PubMed, Scopus, and Google Scholar.
- Keywords included "horse," "equine," "anesthesia," "recovery," "morbidity," and "mortality."
Main Results:
- Recent studies using isoflurane and sevoflurane show fewer intraoperative cardiac arrests compared to older studies with halothane.
- Catastrophic fractures have emerged as the leading cause of mortality during the recovery phase.
Conclusions:
- Modern anesthetic agents have likely contributed to a reduction in intraoperative complications.
- Fracture-related complications during recovery represent a significant and growing concern in equine anesthesia.
Related Concept Videos
01:24Parenteral Anesthetics: Overview
908
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
908
01:24General Anesthesia: Overview
978
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
978
01:22Stages of General Anesthesia
2.2K
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
2.2K
01:20Inhalational Anesthetics: Overview
1.5K
Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
1.5K
01:12Local Anesthetics: Adverse Effects
964
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
964