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Assessing next-generation sequencing and 4 bioinformatics tools for detection of Enterovirus D68 and other
Weihua Huang1, Guiqing Wang2, Henry Lin3
1Department of Pathology, New York Medical College, Valhalla, NY, USA.
Diagnostic Microbiology and Infectious Disease
|March 15, 2016
Abstract:
We used 4 different bioinformatics algorithms to evaluate the application of a metagenomic shot-gun sequencing method in detection of Enterovirus D68 and other respiratory viruses in clinical specimens. Our data supported that next-generation sequencing, combined with improved bioinformatics tools, is practically feasible and useful for clinical diagnosis of viral infections.
