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Related Concept Videos

Larynx01:21

Larynx

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The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
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The Hyoid Bone01:12

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The hyoid bone is a small U-shaped bone located in the upper neck at the level of the inferior mandible, with its tips pointing posteriorly. It does not directly articulate with any other bone in the body. The hyoid acts as the attachment site for the tongue, the larynx, and the pharynx. It is held in position by a series of small muscles attached from above or below. These muscles help to move the hyoid up/down or forward/back in coordination with movements of the tongue, larynx, and pharynx...
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Related Experiment Video

Updated: Mar 24, 2026

Synthetic, Multi-Layer, Self-Oscillating Vocal Fold Model Fabrication
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Nonstimulated rabbit phonation model: Cricothyroid approximation.

Carolyn K Novaleski1, Tsuyoshi Kojima2, Siyuan Chang3

  • 1Department of Hearing and Speech Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, U.S.A.

The Laryngoscope
|March 15, 2016
PubMed
Summary
This summary is machine-generated.

This study introduces a new rabbit model for voice production using Isshiki type IV thyroplasty and airflow. The model successfully generated sustained vocal fold vibration and consistent phonation parameters in vivo.

Keywords:
Rabbit modelphonationvocal fold

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Area of Science:

  • Laryngology
  • Animal Models
  • Voice Production

Background:

  • Developing reliable animal models for voice research is crucial for understanding phonation mechanisms.
  • Previous models often relied on direct neuromuscular stimulation, limiting certain experimental approaches.

Purpose of the Study:

  • To describe a novel nonstimulated in vivo rabbit phonation model.
  • To utilize Isshiki type IV thyroplasty and continuous humidified glottal airflow for sustained audible phonation.

Main Methods:

  • Six rabbits underwent Isshiki type IV thyroplasty and continuous glottal airflow.
  • Phonatory parameters were assessed using high-speed laryngeal imaging, acoustic, and aerodynamic analysis.
  • Post-procedure microimaging confirmed the maintenance of the glottal configuration.

Main Results:

  • Sustained vocal fold oscillation was observed throughout the procedure.
  • Mean vocal intensity was 61 dB and fundamental frequency was 590 Hz.
  • Mean airflow rate was 85.91 mL/s with a subglottal pressure of 9 cm H2O.

Conclusions:

  • A nonstimulated in vivo rabbit phonation model was successfully established.
  • This model produces sustained vocal fold vibration and consistent phonatory measures.
  • The model facilitates geometric reconstruction and validation of computational simulations.