Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

White matter diseases.

M K Edwards1, R R Smith

  • 1Department of Radiology, Indiana University School of Medicine, Indianapolis 46202.

Topics in Magnetic Resonance Imaging : TMRI
|December 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A case report: Hypoxic ischemic encephalopathy & pneumonia in a neonate after SARS-CoV-2 intrauterine transmission.

Journal of neonatal-perinatal medicine·2022
Same author

A web-based review of global health programs in U.S. allopathic and osteopathic medical schools.

Medical teacher·2022
Same author

First Report of Mycoleptodiscus terrestris Infecting Forage Legumes and Soybeans in Wisconsin.

Plant disease·2019
Same author

Experimental studies with Etheron sponge. Effect of implantation in tumor-bearing animals.

Problemy sovremennoi neirokhirurgii·2014
Same author

Chin augmentation: Subperiosteal and supraperiosteal implants.

Aesthetic plastic surgery·2013
Same author

Clinical and bacteriological studies of the use of a fluoride dentifrice.

Journal of dental research·2010
Same journal

Automated Diagnosis of Breast Cancer Using Deep Learning Techniques Applied to Digital Mammography and Magnetic Resonance Images.

Topics in magnetic resonance imaging : TMRI·2026
Same journal

Assessment of Brain Tumor Response to Radiotherapy Using Noninvasive Spectroscopic Magnetic Resonance Imaging Techniques.

Topics in magnetic resonance imaging : TMRI·2026
Same journal

Machine Learning-Based Detection of EGFR Mutation and HER2 Overexpression in Metastatic Brain Adenocarcinoma: Systematic Review and Meta-Analysis.

Topics in magnetic resonance imaging : TMRI·2025
Same journal

Oxygen Saturation, Heart Rate, and Anxiety Levels Among Claustrophobic and Non-Claustrophobic Patients Undergoing Closed and Open MRI: A Comparative Study.

Topics in magnetic resonance imaging : TMRI·2025
Same journal

Preclinical Investigations Toward Gd-free Molecularly Targeted Dual-Modal, MRI Dynamic (DCE-MRI)/Optical Imaging Contrast Agent for Cardiac Angiosarcoma.

Topics in magnetic resonance imaging : TMRI·2025
Same journal

Understanding the Independent Risk Factors of Anterior Shoulder Dislocation Using MRI.

Topics in magnetic resonance imaging : TMRI·2025
See all related articles

Magnetic Resonance Imaging (MRI) detects white matter disease sensitively but lacks specificity. Differentiating causes requires understanding disease patterns, MRI sequences, and crucial clinical history.

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • White matter diseases present significant diagnostic challenges in Magnetic Resonance Imaging (MRI).
  • Lesions on MRI can appear similar across diverse etiologies, including congenital, vascular, infectious, and autoimmune conditions.
  • Current imaging techniques offer high sensitivity but limited specificity for white matter abnormalities.

Purpose of the Study:

  • To highlight the diagnostic limitations of MRI in white matter disease.
  • To emphasize the importance of integrating imaging findings with clinical information.

Main Methods:

  • Review of MRI characteristics of white matter lesions.
  • Analysis of differential diagnoses for white matter abnormalities.
  • Emphasis on the role of clinical history in diagnosis.

Related Experiment Videos

Main Results:

  • MRI is highly sensitive in detecting white matter disease.
  • Specificity remains a challenge due to overlapping imaging features across various diseases.
  • Clinical history is indispensable for accurate diagnosis.

Conclusions:

  • While MRI is crucial for detecting white matter disease, its poor specificity necessitates a comprehensive diagnostic approach.
  • Integrating knowledge of disease patterns and MRI pulse sequences with thorough clinical evaluation is essential for accurate diagnosis.