Related Experiment Video
Updated: Mar 24, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
Insights
Affective disorders are common in patients with coronary artery disease (CAD). Understanding the link between affective and cardiac issues is crucial for developing effective treatments for this prevalent condition.
Area of Science:
- Cardiology
- Psychiatry
- Psychosomatic Medicine
Background:
- Affective disorders frequently co-occur with cardiac diseases, especially coronary artery disease (CAD).
- Affective dysregulation is a significant risk factor for cardiac mortality in CAD patients.
- Current treatment algorithms for affective disorders in cardiac patients are lacking evidence-based guidelines.
Purpose of the Study:
- To propose an etiological model for the interplay between affective and cardiac dysregulation.
- To provide a framework for understanding the relationship between stress and cardiac/affective disorders.
Main Methods:
- Literature review on affective disorders and cardiac disease.
- Development of a theoretical etiological model.
- Application of the stress-diathesis model framework.
Main Results:
- The proposed model integrates psychiatric and cardiac perspectives on dysregulation.
- The stress-diathesis model offers a potential explanation for the co-occurrence of these conditions.
- Highlights the need for integrated treatment approaches.
Conclusions:
- A comprehensive etiological model is needed to address affective disorders in CAD.
- The stress-diathesis model provides a valuable framework for research and clinical practice.
- Further research is warranted to develop evidence-based treatment strategies.
Abstract:
Affective disorders cluster in patients with cardiac diseases, in particular in coronary artery disease (CAD) which has become one of the most prevalent chronic disorders in the western world. Affective dysregulation has been recognized as a major riskfactor for cardiac death in patients with CAD. Therefore treatment of affective dysregulation is important from both the psychiatric and cardiac perspective. An evidence based treatment algorithm for affective disorders is as yet not available. In this paper a possible etiological model for the relationship between affective and cardiac dysregulation is proposed, based on the stress-diathesis model.
More Related Videos
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Cardiomyopathy II: Dilated Cardiomyopathy
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Psychosis: Goals of Pharmacotherapy
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...

