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Updated: Mar 24, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Transfusion supply optimization in multiple-discipline surgical hospital]
I N Solov'eva1, N A Trekova1, I A Krapivkin1
1Acad. B.V. Petrovsky Russian Research Surgery Center, Moscow.
Aim:
To define optimal variant of transfusion supply of hospital by blood components and to decrease donor blood expense via application of blood preserving technologies.
Material And Methods:
Donor blood components expense, volume of hemotransfusions and their proportion for the period 2012-2014 were analyzed.
Results:
Number of recipients of packed red cells, fresh-frozen plasma and packed platelets reduced 18.5%, 25% and 80% respectively. Need for donor plasma decreased 35%. Expense of autologous plasma in cardiac surgery was 76% of overall volume. Preoperative plasma sampling is introduced in patients with aortic aneurysm. Number of cardiac interventions performed without donor blood is increased 7-31% depending on its complexity.
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