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A rare case of true carcinosarcoma of the breast
Antonello Accurso1, Giuseppe Ciancia2, Gianni Antonio Della Corte3
1Department of Gastroenterology, Endocrinology and Surgery, Breast Unit, AOU "Federico II", Via S.Pansini 5, 80131 Naples, Italy.
Background:
True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08-0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transition zone between the two elements.
Case Presentation:
We present a case of a 49-year-old woman presenting with a 4cm mass at the level of her left breast upper-outer quadrant with a histologic diagnosis of true carcinosarcoma of the breast.
Discussion:
The most appropriate therapeutic regimens for breast carcinosarcoma are still unclear because of the rarity of this condition, but Breast Conserving Treatment (BCT) followed by adjuvant chemotherapy seems to provide a prognosis equalling that of usual Invasive Ductal Carcinoma of the breast.
