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Updated: Mar 24, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
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[Spleen-preserving D2 lymphodissection in gastrectomy].

V V Oleksenko1, S V Efetov2, K A Aliev1

  • 1Chair of Oncology, S.I. Georgievskiy Crimean State Medical University, Simferopol.

Khirurgiia
|March 16, 2016
PubMed
Summary

Spleen-preserving D2 lymphodissection in gastric cancer surgery is as effective as standard D2 lymphodissection with splenectomy. This approach reduces postoperative complications while maintaining similar survival rates for patients.

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Area of Science:

  • Surgical Oncology
  • Gastrointestinal Surgery
  • Gastric Cancer Treatment

Context:

  • Gastric cancer necessitates aggressive surgical intervention, often involving extensive lymph node dissection.
  • Total gastrectomy is a common procedure for advanced gastric cancer.
  • The role of splenectomy in D2 lymphodissection for gastric cancer remains a subject of debate regarding its impact on outcomes and complications.

Purpose:

  • To compare the immediate and long-term outcomes of spleen-preserving D2 lymphodissection versus standard D2 lymphodissection with splenectomy in patients undergoing total gastrectomy for gastric cancer.
  • To evaluate the oncological effectiveness and safety profile of spleen-preserving D2 lymphodissection.

Summary:

  • A study of 480 gastric cancer patients undergoing total gastrectomy compared spleen-preserving D2 lymphodissection (371 patients) with standard D2 lymphodissection plus splenectomy (109 patients).
  • Spleen-preserving D2 lymphodissection showed comparable 5-year survival (40.3% vs. 33.1%) and average life expectancy (3.4 vs. 2.7 years).
  • The spleen-preserving technique resulted in a similar incidence of postoperative complications (6.7% vs. 4.6%) and mortality rates (2.7% vs. 0.9%) compared to splenectomy, with no significant difference in the number of retrieved lymph nodes or detection of metastases in key splenic regions.

Impact:

  • Spleen-preserving D2 lymphodissection is a viable and potentially less morbid alternative to standard D2 lymphodissection with splenectomy for gastric cancer.
  • This surgical approach may lead to improved patient recovery and reduced complications without compromising oncological safety.
  • Findings support the adoption of spleen-preserving techniques in gastric cancer surgery, enhancing patient quality of life post-operation.