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[Bleeding and thrombosis – acute complications of liver cirrhosis]

Rupesh Rajani1, Hanns-Ulrich Marschall2

  • 1Gastrocentrum - Sektionen för Hepatologi Stockholm, Sweden Gastrocentrum - Sektionen för Hepatologi Stockholm, Sweden.

Lakartidningen
|March 16, 2016
PubMed

Patients with acute and chronic liver disease have a rebalanced hemostasis, i.e. these patients have an increased tendency for both bleeding and thrombosis.Bleeding is primarily related to portal hypertension, rather than a defective hemostasis. There are well-established clinical guidelines for the management of patients with liver cirrhosis and variceal bleeding.Epidemiological studies have demonstrated an increased risk of venous thromboembolism in patients with liver cirrhosis. The treatment of patients with liver cirrhosis and venous thrombosis is not well documented. Treatment with anticoagulants should be considered in patients with symptomatic, extensive or progressive thrombosis of the portal system, as well as in patients who are being considered for liver transplantation.

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