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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Asthma 2015: The Year in Review.

Bruce K Rubin1

  • 1Department of Pediatrics, Virginia Commonwealth University School of Medicine, Children's Hospital of Richmond, Richmond, Virginia. bruce.rubin@vcuhealth.org.

Respiratory Care
|March 17, 2016
PubMed
Summary

Asthma research saw over 6,500 publications in 2015. This review highlights key studies, noting conflicting findings and ongoing questions in asthma management and treatment.

Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Respiratory Medicine

Background:

  • Over 6,500 peer-reviewed papers on asthma were published between January 2015 and October 2015.
  • The field of asthma research is dynamic and rapidly evolving.
  • New asthma medications are anticipated in the coming years.

Purpose of the Study:

  • To review and synthesize significant research advancements in asthma published in 2015.
  • To identify key themes and emerging trends in asthma literature.
  • To highlight areas of scientific debate and future research directions in asthma.

Main Methods:

  • A curated selection of peer-reviewed asthma publications from PubMed (January 2015 - October 2015).
  • Thematic organization of selected studies based on reviewer interest.
Keywords:
aspirinasthmainhalersobesitypregnancy

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  • Analysis of selected literature for conflicting findings and unresolved questions.

    • Main Results:

    • The selected studies cover diverse aspects of asthma research.
    • Some reviewed papers presented conflicting results, indicating ongoing scientific discourse.
    • Several studies raised new questions, underscoring the complexity of asthma.

    Conclusions:

    • 2015 was a highly active year for asthma research.
    • The volume and nature of publications suggest continued intense interest in asthma.
    • Future advancements in asthma treatment are expected with new medications.