Related Experiment Video
Updated: Mar 24, 2026

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
Published on: May 26, 2015
A Practical Method for No-Reflow Treatment
Mustafa Cetin1, Emrullah Kiziltunc1, Zehra Güven Cetin2
1Cardiology Department, Numune Education and Research Hospital, Cardiology Department, 06100 Ankara, Turkey.
Insights
No-reflow, a complication of coronary interventions, can be successfully treated. A repurposed monorail balloon served as a distal infusion catheter for vasoactive drugs, effectively managing no-reflow in two cases.
Area of Science:
- Interventional Cardiology
- Vascular Medicine
Background:
- No-reflow is a significant complication following percutaneous coronary interventions.
- Distal administration of vasoactive drugs is a potential therapeutic strategy for no-reflow.
- Existing methods for distal drug delivery can be complex or unavailable.
Purpose of the Study:
- To describe a novel, simple method for distal vasoactive drug infusion in managing no-reflow.
- To present two case studies demonstrating the successful application of this technique.
Main Methods:
- A previously used monorail balloon was adapted as a hand-made distal infusion catheter.
- Vasoactive drugs were administered distally via the repurposed catheter during percutaneous coronary intervention.
- Two patients experiencing no-reflow were treated using this method.
Main Results:
- Successful management of the no-reflow phenomenon in both treated cases.
- The hand-made distal infusion catheter facilitated effective drug delivery to the affected coronary artery segment.
- The procedure was technically feasible and well-tolerated by the patients.
Conclusions:
- Repurposing a monorail balloon as a distal infusion catheter is a viable and effective strategy for managing no-reflow.
- This technique offers a practical solution for distal drug delivery in challenging interventional cardiology scenarios.
- Further investigation into this method could optimize no-reflow treatment protocols.
Abstract:
No-reflow is an undesirable result of percutaneous coronary interventions. Vasoactive drug administration at the distal part of the coronary artery is suggested as a therapeutic option for no-reflow treatment. Here, we represent two cases of successful no-reflow management with previously used monorail balloon at the same procedure as a hand-made distal infusion catheter.
More Related Videos
05:26Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
06:25Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
Published on: March 15, 2020