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Draft genome sequence of a multidrug-resistant Chryseobacterium indologenes isolate from Malaysia

Choo Yee Yu1, Geik Yong Ang1, Huey Jia Cheng1

  • 1Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Genomics Data
|March 17, 2016
PubMed

Insights

Chryseobacterium indologenes is a multidrug-resistant pathogen causing healthcare-associated infections. This study reports the draft genome of a Malaysian strain, identifying antibiotic resistance genes that explain its resistance mechanisms.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Chryseobacterium indologenes is an emerging pathogen associated with nosocomial infections.
  • Its multidrug-resistant (MDR) phenotype poses a significant threat in clinical settings.

Purpose of the Study:

  • To report the draft genome sequence of a multidrug-resistant Chryseobacterium indologenes strain.
  • To identify potential antibiotic resistance determinants within the genome.

Main Methods:

  • Whole-genome sequencing of Chryseobacterium indologenes CI_885.
  • Bioinformatic analysis to identify antibiotic resistance genes.

Main Results:

  • The draft genome size is 908,704 kb.
  • The genome contains numerous putative antibiotic resistance determinants.
  • The strain CI_885 was isolated from Malaysia in 2014.

Conclusions:

  • The genome sequence provides insights into the molecular basis of MDR in Chryseobacterium indologenes.
  • Understanding these resistance mechanisms is crucial for developing effective treatment strategies against this pathogen.
Keywords:
Chryseobacterium indologenesGenomeMulti-drug resistantNext generation sequencingblaIND

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