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Sentinel lymph node biopsy under fluorescent indocyanin green guidance: Initial experience.
Fatih Aydoğan1, Akif Enes Arıkan2, Erman Aytaç2
1Department of General Surgery, Breast Diseases Service, İstanbul University, Cerrahpaşa Medical Faculty İstanbul, Turkey.
Ulusal Cerrahi Dergisi
|March 18, 2016
Summary
Sentinel lymph node biopsy using fluorescent indocyanine green (ICG) is a feasible technique for breast cancer staging. This method allows for simultaneous visualization and guidance during surgery, proving effective in identifying metastatic lymph nodes.
Area of Science:
- Oncology
- Surgical Oncology
- Medical Imaging
Background:
- Sentinel lymph node biopsy (SLNB) is a standard procedure for breast cancer staging.
- Traditional SLNB methods include blue dye and radionuclide tracers.
- Fluorescent imaging offers a novel approach for SLNB.
Purpose of the Study:
- To evaluate the applicability and feasibility of SLNB using fluorescent indocyanine green (ICG).
- To assess the efficacy of ICG in identifying sentinel lymph nodes in breast cancer patients.
Main Methods:
- The IC-VIEW infrared visualization system was utilized.
- Indocyanine green (2 mL) was injected to visualize sentinel lymph nodes.
- Sentinel lymph nodes were identified, excised under fluorescent guidance, and examined histopathologically.
Main Results:
- Sentinel lymph nodes were successfully visualized in all four included breast cancer patients using ICG.
- The median number of excised sentinel lymph nodes was 2.
- Two patients with confirmed lymph node metastasis underwent successful axillary dissection without complications.
Conclusions:
- Sentinel lymph node biopsy guided by fluorescent indocyanine green is technically feasible.
- The method offers simultaneous visualization, aiding in accurate lymph node identification.
- This technique shows promise for breast cancer staging with minimal complications.
