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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Synthesis, characterization, molecular modeling, and potential antimicrobial and anticancer activities of novel

Hany Emary Ali Ahmed1, Hassan A Abdel-Salam2, Mohamed A Shaker3

  • 1Pharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, P.O. Box 30039, Al-Madinha Al-Munawaraha 41477, Saudi Arabia; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, P.O. Box 11651, Cairo 11884, Egypt.

Bioorganic Chemistry
|March 18, 2016
PubMed

Keywords:
2-Aminoisoindoline-1,3-dioneAnticancer activitySciff baseStructure-selectivity relationships

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