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Updated: Mar 24, 2026

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Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes
Published on: October 15, 2016
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A business of some heat: molecular imaging of phosphodiesterase 5
Paul Cumming1,2
1Department of Neuropsychiatry and Psychosomatic Medicine, Oslo University Hospital, Oslo, Norway.
Journal of Neurochemistry
|March 19, 2016
Abstract
No abstract available in PubMed .
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The addition or removal of phosphate groups from proteins is the most common chemical modification that regulates cellular processes. These modifications can affect the structure, activity, stability, and localization of proteins within cells as well as their interactions with other proteins.
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Phosphodiester bond forms when a phosphoric acid molecule (H3PO4) links with two hydroxyl groups (–OH) of two other molecules, forming two ester bonds. Two water molecules are released in this process. The phosphodiester bond is commonly found in nucleic acids (DNA and RNA) and plays a critical role in their structure and function.
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