Accuracy of the simplified Bernoulli relationship in measuring pressure gradients across stenosis

In order to test the validity of the modified Bernoulli equation in predicting pressure gradients across stenotic regions, we have constructed an in-vitro model and studied the influence of the length and of the severity of the stenosis. Under physiological conditions, simultaneous pressure gradients are estimated by both Doppler and direct pressure manometer techniques. Measurements of the pressure gradients (in the range 10-150 mmHg) by the two techniques show that the Doppler estimation using the modified Bernoulli equation underestimated the pressure transducer gradient measurements for every length of stenosis, this underestimation being greater than 45% for very severe stenosis.