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[Pruritus in chronic kidney insufficiency].

A Bruni1, E Dos Ramos Farias, R Heguilen

  • 1Departamento de Medicina, Hospital Italiano de Buenos Aires, Argentina.

Medicina Cutanea Ibero-Latino-Americana
|January 1, 1989
PubMed
Summary

Itching is common in chronic renal failure patients. Older age and reduced urine output are linked to itching, while higher hematocrit levels in men may be protective.

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Area of Science:

  • Nephrology
  • Dermatology
  • Pathology

Context:

  • Itching (pruritus) is a prevalent symptom in patients with chronic renal failure (CRF).
  • This study investigated the prevalence and potential correlates of pruritus in 80 patients with end-stage renal disease (ESRD).

Purpose:

  • To identify factors associated with itching in patients undergoing treatment for end-stage renal disease.
  • To explore potential correlations between pruritus and clinical, laboratory, and histological findings.

Summary:

  • Itching was present in 56.3% of ESRD patients studied.
  • No correlation was found between itching and duration of hemodialysis, or levels of calcium, phosphorus, alkaline phosphatase, or the phosphocalcic product.
  • Key associations identified include older age, residual diuresis < 500 ml/day, and increased frequency of histological findings in patients with pruritus. Men without itching exhibited higher hematocrit levels.

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Impact:

  • Highlights the prevalence of itching in ESRD and identifies specific patient characteristics associated with this symptom.
  • Suggests that age, residual renal function, and histological changes may play a role in the development of pruritus.
  • Provides insights for further research into the pathophysiology and management of uremic pruritus.