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Updated: Mar 24, 2026

Culture of Neurospheres Derived from the Neurogenic Niches in Adult Prairie Voles
Published on: June 10, 2020
Social behavior, hormones and adult neurogenesis
Maya Opendak1, Brandy A Briones1, Elizabeth Gould1
1Department of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Abstract:
A variety of experiences have been shown to affect the production of neurons in the adult hippocampus. These effects may be mediated by experience-driven hormonal changes, which, in turn, interact with factors such as sex, age and life history to alter brain plasticity. Although the effects of physical experience and stress have been extensively characterized, various types of social experience across the lifespan trigger profound neuroendocrine changes in parallel with changes in adult neurogenesis. This review article focuses on the influence of specific social experiences on adult neurogenesis in the dentate gyrus and the potential role of hormones in these effects.
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