Five years renal transplantation data: Single-center experience from Iraq

Area of Science:

• Nephrology
• Transplantation Medicine
• Public Health

Background:

• Renal transplantation is the primary treatment for end-stage renal disease.
• Iraq's renal transplant program, initiated in 1973, relies solely on live donors due to the absence of a deceased donor program.
• Long-term data on renal transplantation in Iraq are limited.

Purpose of the Study:

• To present data on renal transplantation and one-year medical follow-up.
• To conduct a survival analysis at one, three, and five years post-transplantation.
• To evaluate the outcomes of renal transplantation in Iraq.

Main Methods:

• A retrospective analysis of 250 renal transplantations performed between January 2009 and January 2014.
• Utilized a living donor, blood group compatible donor program.
• Employed triple immunosuppression (calcineurine inhibitor, mycophenolate mofetil/mycophenolic acid, and steroid).
• Determined survival rates using the Kaplan-Meier method.

Main Results:

• One-year graft survival was 98.9% for related and 91.8% for unrelated donors.
• Graft survival decreased to 82.9% in patients experiencing acute rejection.
• One-year patient survival was 94%.
• Three-year graft and patient survival rates were 91% and 90%, respectively.
• Five-year graft and patient survival rates were 87.1% and 88%, respectively.

Conclusions:

• Renal transplantation outcomes in Iraq are demonstrating improvement.
• Enhanced long-term patient follow-up is essential.
• Establishing a renal transplant registry is critical for future planning.
• Increased social, religious, and governmental support is needed for renal transplantation in Iraq.