Related Experiment Video
Updated: Mar 23, 2026
08:22
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
5.5K
Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography
J Howlett1, K Vahdani1, J Rossiter1
1Department of Ophthalmology, Musgrove Park Hospital, Taunton, Somerset, United Kingdom.
Journal of Current Glaucoma Practice
|March 22, 2016
Summary
Bulbar conjunctival and Tenon's layer thickness varies significantly between individuals, impacting glaucoma surgery outcomes. Optical coherence tomography (OCT) can measure these layers to predict bleb function and guide treatment.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Ophthalmic Imaging
Background:
- Variability in bulbar conjunctiva and Tenon's layers thickness observed during glaucoma surgery.
- Potential influence of these tissue layers on the morphology and function of filtration blebs.
Purpose of the Study:
- To pilot a study assessing bulbar conjunctival and Tenon's layer thickness.
- Utilize optical coherence tomography (OCT) for precise measurements.
- Correlate tissue thickness with potential bleb outcomes.
Main Methods:
- Pilot study involving 67 eyes from 48 individuals.
- Optical coherence tomography (OCT) (Optovue Mode RT100) used for imaging.
- Combined bulbar conjunctival and Tenon's layer thickness measured 3 mm superior to the limbus.
Main Results:
- Mean combined thickness was 393 ± 67 microns (range: 194–573 microns).
- Significant inter-individual variation in thickness was observed.
- Patient demographics: age 23–91 years, 20 males, 28 females.
Conclusions:
- OCT measurements reveal substantial variation in conjunctival and Tenon's layer thickness.
- This variability may predict bleb encapsulation, failure, or thin avascular blebs.
- Further research could establish cut-offs for intraoperative interventions like antimetabolites or Tenon's excision.
