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Related Experiment Video

Updated: Mar 23, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Prostate cancer markers: An update.

Srinivas Pentyala1, Terry Whyard2, Sahana Pentyala3

  • 1Department of Anesthesiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA; Department of Urology, Stony Brook Medical Center, Stony Brook, NY 11794, USA; Department of Health Sciences, Stony Brook Medical Center, Stony Brook, NY 11794, USA; Department of Physiology, Stony Brook Medical Center, Stony Brook, NY 11794, USA.

Biomedical Reports
|March 22, 2016
PubMed
Summary
This summary is machine-generated.

Early detection of prostate cancer is critical for American men, as it is the most common malignancy and second leading cause of cancer death. This review updates on prostate cancer biomarkers and highlights the need for more specific and effective diagnostic tools.

Keywords:
Gleason scoresbiomarkersmetastasisprostate cancerprostatectomy

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Area of Science:

  • Oncology
  • Urology
  • Biomarker Research

Background:

  • Prostate cancer is the most common cancer in American men, accounting for 29% of diagnoses.
  • It is the second leading cause of cancer-related death in American men.
  • Early-stage prostate cancer is often asymptomatic, making early detection crucial.

Purpose of the Study:

  • To provide an update on the current landscape of prostate cancer biomarkers.
  • To discuss potential future directions in prostate cancer biomarker discovery.

Main Methods:

  • Review of existing literature on prostate cancer detection methods.
  • Analysis of current prostate cancer biomarkers.
  • Discussion of emerging biomarker research.

Main Results:

  • Common detection methods include digital rectal exam, transrectal ultrasound, and biomarkers.
  • While research is abundant, a need exists for more specific and effective biomarkers.
  • Current biomarkers may not always indicate early-stage disease.

Conclusions:

  • Early diagnosis of prostate cancer is essential for improved patient outcomes.
  • Novel biomarkers with enhanced specificity and efficacy are needed.
  • Continued scientific inquiry into prostate cancer biomarkers is warranted.