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Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
Published on: September 6, 2024
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Design of a hydrophobic tripeptide that self-assembles into amphiphilic superstructures forming a hydrogel
A V Vargiu1, D Iglesias, K E Styan
1University of Cagliari, Department of Physics, S. P. Monserrato-Sestu Km. 0.700, 09042 Monserrato, CA, Italy.
Abstract:
We report the rational design of a heterochiral hydrophobic tripeptide self-assembling into amphiphilic d-superstructures that yield a self-supportive hydrogel at physiological pH. The material endures cell culture conditions and sustains fibroblast proliferation. Tripeptide superstructures are thoroughly analysed by several techniques.

