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Low-Flow Vascular Malformation Pitfalls: From Clinical Examination to Practical Imaging Evaluation--Part 1, Lymphatic
Candace L White1, Brandon Olivieri1, Ricardo Restrepo2
11 Department of Radiology, Mount Sinai Medical Center of Florida, Miami Beach, FL.
Insights
Pediatric subcutaneous masses, often lymphatic malformations, can mimic other soft-tissue pathologies. This review highlights their varied presentations and imaging features to aid diagnosis in children.
Area of Science:
- Pediatric Radiology
- Vascular Anomalies
- Diagnostic Imaging
Background:
- Subcutaneous masses are common in children, presenting diverse etiologies.
- Lymphatic and venous malformations are frequent causes of pediatric subcutaneous lesions.
- Differential diagnosis includes congenital/acquired, benign/malignant soft-tissue masses mimicking vascular malformations.
Purpose of the Study:
- To review the natural history and clinical presentations of pediatric lymphatic malformations.
- To describe the characteristic imaging appearance of lymphatic malformations.
- To highlight differentiating features of pediatric soft-tissue pathologies that mimic lymphatic malformations.
Main Methods:
- Review of literature on pediatric lymphatic malformations and mimickers.
- Analysis of clinical and imaging characteristics.
- Emphasis on diagnostic clues for accurate identification.
Main Results:
- Lymphatic malformations exhibit a wide range of clinical presentations.
- Characteristic imaging findings aid in diagnosing lymphatic malformations.
- Certain pediatric soft-tissue pathologies can closely mimic lymphatic malformations.
Conclusions:
- Accurate diagnosis of pediatric subcutaneous masses requires understanding lymphatic malformations and their mimics.
- Imaging plays a crucial role in differentiating lymphatic malformations from other soft-tissue pathologies.
- Recognizing subtle clinical and imaging clues is essential for proper diagnosis.
Objective:
Palpable subcutaneous masses present in various shapes and sizes in the pediatric population and, accordingly, represent a variety of underlying causes. Lymphatic and venous malformations are among the most common pediatric subcutaneous lesions. However, there are congenital and acquired, as well as benign and malignant, soft-tissue masses that can mimic them clinically and at imaging.
Conclusion:
Here, we review the natural history, wide range of clinical presentations, and varied but characteristic imaging appearance of lymphatic malformations that can pose diagnostic difficulties in children. In addition, the clinical and imaging characteristics of some pediatric soft-tissue pathologies that can mimic lymphatic malformations and clues to reach a proper diagnosis are highlighted.
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