Related Experiment Video
Updated: Mar 23, 2026
09:33
Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
7.9K
[THE POSSIBILITY OF APPLICATION OF COLORIMETRY TECHNIQUE OF DETECTION OF LEVELS OF OXIDATIVE STRESS AND ANTIOXIDANT
Klinicheskaia Laboratornaia Diagnostika
|March 23, 2016
Summary
Oxidative stress increases with age, while antioxidant capacity declines. Bronchopulmonary diseases are linked to high oxidative stress and low antioxidant defense, indicating a significant impact on health.
Area of Science:
- Biochemistry
- Clinical Chemistry
- Gerontology
Context:
- Oxidative status and antioxidant capacity are key biomarkers.
- Colorimetry was used to detect peroxides in blood serum.
- Study included healthy individuals across age groups and patients with bronchopulmonary pathology.
Purpose:
- To analyze serum oxidative status and antioxidant capacity in different populations.
- To correlate these biochemical markers with age and health conditions.
- To understand the role of oxidative stress in bronchopulmonary diseases.
Summary:
- Younger individuals (17-20 years) exhibited low oxidative stress and high antioxidant capacity.
- Older adults (30-60 years) showed increased oxidative stress and decreased antioxidant defense with age.
- Patients with bronchopulmonary pathology consistently presented with high oxidative stress and low antioxidant defense.
Impact:
- Establishes a link between aging, oxidative stress, and reduced antioxidant capacity.
- Highlights the significant oxidative burden in bronchopulmonary diseases.
- Provides quantitative data supporting the relationship between biochemical markers and health status.
